HEART Score – yes, AGAIN! going to keep mentioning it until everyone uses it!

The HEART score is a risk stratification score for identifying the risk of a Major Adverse Coronary Event (MACE) within 6 weeks of presentation that has been validated for the ED population.  (MACE defined as: All Cause Mortality, Myocardial Infarction, or Coronary revascularization).  All those framingham risk factors that we are forced to memorize and that cardiologists always ask about?  They mean almost nothing for ED patients.  Wonderful for the patients who go to their PCP’s on a regular basis, but in terms of people who present to the ED, using risk factors as the sole predictor of badness is probably worse than just flipping a coin.

Well, about about TIMI score?  Isn’t that validated?  YES, it is validated, but doesn’t perform nearly as well for ED patients as the HEART score.  Also, TIMI was derived for  “patients admitted and anticoagulated for concerning chest pain in the setting of ECG changes, known coronary artery disease, or positive biomarkers. The original predictive value of the TIMI Score was intended to prognosticate 14-day mortality or new cardiac ischemia for cardiac inpatients.” (ACEP Now).  I’m pretty sure all of us can stratify patients as moderate to high risk if they are already admitted and on anticoagulation.

Backus et. al compared the c-statistic of the HEART Score, GRACE Score, and TIMI for ED patients.  A c-statistic is used to predict the probability that an outcome is greater than chance.  Values are from 0.5 – 1.0, with a value of 0.5 meaning it is no better than chance. 0.7 is considered a reasonable score and 0.8 is considered strong.

GRACE: 0.70

TIMI: 0.75

HEART: 0.83

So basically GRACE is okay, but so complex to use and so many variables that it’s nearly impractical to use.  TIMI was derived initially for patients with known ACS, but has been found to be acceptable to use for ED patients.

But the HEART score was created specifically to be used for ED patients, AND it outperforms the other scores.

There is also the EDACS (Emergency Department Assessment of Chest Pain Score) that may outperform the HEART score, but I personally find it to have too many variables.  Not nearly as many as GRACE, but still a lot.  Click Here if you want to play around with it.

If you have not memorized the HEART score, This link can help you out.

I have also added a smart phrase in epic (.HEARTSCORE) for everyones convenience.  Please let me know if it does not work for you.

Please vote in the poll and please share your thoughts in the comment section.

Thank you!

Some links:



Backus, B E, A J Six, J C Kelder, M A R Bosschaert, E G Mast, A Mosterd, R F Veldkamp, et al. 2013. A prospective validation of the HEART score for chest pain patients at the emergency department. International journal of cardiology, no. 3 (March 7). doi:10.1016/j.ijcard.2013.01.255.http://www.ncbi.nlm.nih.gov/pubmed/23465250.

http://mchp-appserv.cpe.umanitoba.ca/viewDefinition.php?definitionID=104234 (if for some reason you want to learn more about what a c-statistic is)



Should beta blockade be part of the ED protocol for patients with Acute Coronary Syndrome?

I’m pretty sure everyone agrees beta blockade has significant benefit on patients with heart disease.  However, when is the best time to give the beta blocker?  Within the first hour?  24 hours?  Month?  Should beta blockade be given intravenously?  or orally?

UpToDate’s summary recommends: “For all patients with acute MI, we recommend initiation of oral beta blockers within the first 24 hours, as long as no contraindications are present. (Grade 1B). ”

The 2013 ACCF/AHA STEMI Management Guidelines give a Class 1 recommendation to starting oral beta blockers within 24 hours of presentation, but a class 2a recommendation to give IV beta blockade at time of presentation to those “who are hypertensive and have ongoing ischemia.”  (https://circ.ahajournals.org/content/127/4/e362.full)

Please post your thoughts below by clicking on the “reply” button.